文章資訊：組織因子途徑抑制劑抗體

  實驗類型：WB,IHC-P,IHC-F,IF,ELISA

  應(yīng)用范圍：Mouse,Rat (predicted: Human,Pig,Cow,Horse,Rabbit)

  注：古朵生物公司產(chǎn)品僅供科研研究實驗，不得用于臨床!

  商品詳情：

  英文名稱：TFPI

  中文名稱：組織因子途徑抑制劑抗體

  別 名;Tissue factor pathway inhibitor; Tissue factor pathway inhibitor-1; convertin; EPI; Extrinsic pathway inhibitor; LACI; Lipoprotein associated coagulation inhibitor; TFI; TFPI 1; TFPI1; TFPI1_HUMAN.

  研究領(lǐng)域;心血管

  抗體來源;Rabbit

  克隆類型;Polyclonal

  交叉反應(yīng);Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Rabbit, )

  產(chǎn)品應(yīng)用;WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))

  not yet tested in other applications.

  optimal dilutions/concentrations should be determined by the end user.

  理論分子量;32kDa

  細胞定位;分泌型蛋白

  性 狀;Liquid

  濃 度;1mg/ml

  免 疫 原;KLH conjugated synthetic peptide derived from human TFPI: 101-200/304

  亞 型;IgG

  純化方法;affinity purified by Protein A

  緩 沖 液;0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

  保存條件;Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

  注意事項;This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

  產(chǎn)品介紹;TFPI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins.

  Function:

  Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma.

  組織因子途徑抑制劑抗體 上海古朵生物科技有限公司成立于上海浦東新區(qū)。是一家專門從事生物技術(shù)相關(guān)產(chǎn)品，勵志研發(fā)和銷售的綜合性生物公司，產(chǎn)品遠銷多個國家和地區(qū)，我們將一如既往地秉承“一切為了滿足客戶的需求"的經(jīng)營宗旨;牢固樹立“以客戶需求為準則、以市場需求為導向，不斷開發(fā)高質(zhì)量的新產(chǎn)品，提供客戶滿意的綜合服務(wù)質(zhì)量"的方針。